hrp0097p1-573 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Testosterone therapy in Duchenne Muscular Dystrophy and longitudinal bone growth with metacarpophalangeal index

McCauley Cara , Dunne Jennifer , Horrocks Iain , Joseph Shuko , Choong Wong Sze

Background: Testosterone therapy is recommended for management of puberty from the age of 12 years in boys with Duchenne Muscular Dystrophy(DMD) in accordance with the 2018 international standards of care. The majority of boys loose ambulation in mid to late adolescence. Height measurement is problematic in these adolescents s as lower limb contracture can be common and estimated height from segmental body part measurements generally over-estimate height.<...